Picking Pyknons out of the Human Genome
نویسندگان
چکیده
In a recent paper in PNAS, Rigoutsos et al. (2006) describe a nonrandom pattern of repeated elements, called pyknons, which are found more frequently in the 3' untranslated regions of genes than in other regions of the human genome. Although it is unclear how pyknons might have arisen, it is possible that they may be involved in a new form of gene regulation.
منابع مشابه
Short blocks from the noncoding parts of the human genome have instances within nearly all known genes and relate to biological processes.
Using an unsupervised pattern-discovery method, we processed the human intergenic and intronic regions and catalogued all variable-length patterns with identically conserved copies and multiplicities above what is expected by chance. Among the millions of discovered patterns, we found a subset of 127,998 patterns, termed pyknons, which have additional nonoverlapping instances in the untranslate...
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عنوان ژورنال:
- Cell
دوره 125 شماره
صفحات -
تاریخ انتشار 2006